Committee Composition Audit Committee Compensation Committee Nominating and Corporate Governance Committee Fred E. Cohen, M.D., D.Phil. Compensation Committee Lloyd Dean Nominating and Corporate Governance Committee Kevin Gordon Audit Committee Nominating and Corporate Governance Committee Roger Holstein Compensation Committee Jeff Park Audit Committee Compensation Committee Norman Payson, M.D. Audit Committee Nominating and Corporate Governance Committee Cheryl Scott Nominating and Corporate Governance Committee Beth Seidenberg, M.D. Compensation Committee = Independent Director = Chairperson = Member = Financial Expert